Nutrient detection by incretin hormone secreting cells
نویسندگان
چکیده
منابع مشابه
Nutrient detection by incretin hormone secreting cells
The hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulintropic polypeptide (GIP) are secreted after a meal. Like other enteroendocrine hormones they help to orchestrate the bodies' response to the availability of newly absorbable nutrients and are noteworthy as they stimulate postprandial insulin secretion, underlying what is known as the incretin effect. GLP-1-mimetics are no...
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Incretin peptides (glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)) are secreted from enteroendocrine cells in the intestinal epithelium, and help to coordinate metabolic responses to food ingestion. A number of molecular mechanisms have recently been defined that underlie carbohydrate, lipid and protein sensing in gut endocrine cells. Knockout mice lackin...
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ژورنال
عنوان ژورنال: Physiology & Behavior
سال: 2012
ISSN: 0031-9384
DOI: 10.1016/j.physbeh.2011.12.001